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Questions related to Bioinformatics and Computational Biology
Dear All, I have executed >1000 drug molecules in a Vina docking study. Now I have >1000 log files that contain the top ten binding scores for every compound in a log file for each. I want to...
07 November 2022 739 3 View
I have docked two proteins through GRAMM-X Protein-Protein Docking Web Server. Now, I want to perform MD simulation of the docked protein-protein complexes. I will be highly appreciated it if...
27 October 2022 5,735 3 View
I am interested to find interactions between plant wax and other chemical compounds. Is there any computational tool or webserver to find the interactions? Thank you
21 October 2022 9,761 4 View
I have... Independent variables :- 1. Seasons (Season 1 and season 2) 2. Treatments (6 groups) Dependent variable:- Number of grains Which statistical test in SPSS should I use? When I tried to...
17 October 2022 6,799 3 View
As usual Good quality Peer reviewed Reasonable APC (need not sell my kidneys for a paper) or Free Rapid review Good acceptance (not reject with universal stupid Submission declined...
15 October 2022 7,394 6 View
I have isolated svf from adipose tissues and will be characterising the macrophage using facs. I need to grow the isolated macrophages and need optimised protocol.
04 August 2022 6,324 1 View
Hi, I am working on cancer biomarker sensing. In CA 125-based sensing, the authors have mentioned the LOD in U/mL. I would like to know how to convert U/mL to gram or molar.
26 July 2022 1,792 0 View
Hi, I am conducting a research that aims to determine the biodiversity of Nudibranch in the intertidal and subtidal zone.
29 May 2022 8,127 2 View
For my research on the detection of Cr (VI), I must dilute my solution 3 times using 2 fold serial dilution to be able to analyze it with a UV spectrophotometer. So, I can calculate the 3 times...
22 April 2022 3,861 5 View
I have completed my molecular dynamics (MD) on three complexes and protein alone. All the three complexes have Higher RMSD value than the protein alone. How can we justify this Higher RMSD of...
10 April 2022 7,415 2 View
Autodock Vina- Error in docking
21 December 2021 6,804 1 View
Hello, I have been recently analyzing targeted exome sequencing data and have been using in silico tools such as SIFT, PolyPhen-2 etc for variant prediction. However, I am finding it difficult to...
07 April 2021 3,254 3 View
I have minimal knowledge when it comes to nudibranch as I have just recently been interested in it. I would like to know if there is some sort of guidelines when it comes to nudibranch sampling...
21 January 2021 2,089 0 View
When I load repeat simulation of my mutated protein from 10ns-20ns-30ns, its RMSD graph is in picture. I watched my dcd, my protein goes out of the water box. I tried to put it inside of the box...
15 May 2020 719 6 View
Few of us wanted to create a discord server for Biophysics. What we intend is to begin a commonplace for discussions/numerical experiments. Also possibly document the results in the form of blogs...
02 April 2020 7,345 3 View
I am working on FIV and have sequenced each gene individually and retrieved multiple complete genomes and individual genes from Genbank. I am trying to align all the different genes to the...
03 March 2020 1,728 1 View
Hi everyone! I've been study the expression of 5 microRNAs using TaqMan assays in several cell lines (microRNAs were selected through literature review) and I obtained statistically significant...
02 February 2020 7,712 3 View
Hi, Can anyone please explain me how to use Genscan tool to find exons and introns for a given gene sequence? I want to calculate sensitivity and specificity to check its performance for a given...
31 December 2019 2,343 3 View
Hi! I've been using the refine.bio website to download normalized transcriptome data; each downloaded dataset consists in a compressed directory with an expression matrix in .tsv format, its...
12 December 2019 6,466 2 View
12 December 2019 5,083 3 View
05 December 2019 3,910 2 View
I am looking for databases that contain microRNA-drug interactions. Any suggestions or recommendations?
31 October 2019 2,628 3 View
Help appreciated!! We are having Empirical data sets of plant barcodes (matK, ITS and rbcL), and want to compare analytical methodology used for Empirical data sets with the Synthetic data...
25 September 2019 7,712 7 View
Hello, After reading the infamous publication "More Bang for your Bucks", I developed a workstation of my own using Xeon CPU (>3GHz, E5 series) along with one RTX and one GTX GPUs. In case of...
16 September 2019 2,141 7 View