Ribozymes

Hi Muneeb, "chosen" is a loaded word.

It could imply divine intervention, supernatural forces or even alien influence.

Sometime ago I read that certain clay materials bind ribose and nucleotides in a chiral dependent manner. I haven't followed these studies, but if they have any validity, they should follow Darwinist principles.

Those RNAs that survive the primitive earth conditions were either stable enough or were able to synthesized more copies than were destroyed.

After that, I have no clue.

Hi Stefansson.

Thanks for the reply.

I think the word "chosen" has a metaphoric use here. May be it would mean chosen by evolution (or the underlying principles of evolution) rather than divine evolution. Nevertheless, my question is actually different. I think it asks for enumeration of advantages of RNA as a genetic material under the primitive conditions.

Thanks for the answer anyway!

OK, point taken.

Entropy is a problem. Is it possible that RNA requires no energy to be produced by a clay-like chiral template that specifically binds chiral molecules?

There has to be a chiral quasi-enzyme/template responsible for the generation of chiral biomolecules.

Clay can acts like a quasi-enzyme by bringing all of the chiral components in a high enough concentrations of ribose and nucleotides in a small enough space to react spontaneously. In chemistry and biochemistry it is well established that if you concentrate reactive compounds in a small volume, any bonds that are possible to form will form.

RNA can form loop structures that are stable that could unwind and replicate on a solid surface.

After that I have no idea.