MInimisation before docking?

I am trying to do both docking and molecular dynamics simulation. Should I minimise the protein structure after adding amino acids far from active site before docking? I have taken a PDB structure...

02 November 2020 4,798 4 View

SENP1 treatment of CoImmunoprecipiteted proteins?

Dear Researcher, I am trying to imminoprecipitate (IP) Sumoylated protein. i am succesfully able to get it. now i have to carry out desumoylation of that immunoprecipiteted proteins in vitro. I...

27 February 2017 6,419 3 View

May I know somebody interested to collaborate in academic work about 'Adolescent SRH in Nepal (a quantitative study'?

27 January 2017 413 4 View

No title

10 January 2017 3,671 1 View

Can anyone suggest a simple calculation procedure to prepare any solution in terms of ppm ?

I am very confident and experienced enough in preparing the solutions up to ppm level when it is a SOLID, but I am confused in the case of LIQUIDS, say for example Hexadecane (hydrocarbon) has...

16 February 2015 9,202 18 View

Does use of a variable speed drive always ensure energy saving at reduced speed?

Vsd during running would result into some losses in terms of heat..my doubt is whether energy saving can be achieved at every range of reduced speed ( say @95%) considering those losses?

17 May 2014 6,855 4 View

Radiation from a porous region?

I am modelling porous medium combustion in FLUENT with a separate energy equation for the fluid and the solid zone. Since the temperature of the solid region is quite high (around 1200 K),...

11 February 2014 4,012 3 View

Do you know of a mesh based micro structure representation algorithm?

I wish to represent physical phase boundaries in a porous structure on a mesh. It seems to be quite simple to get a porous structure with the desired porosity by mere random allocation of solid...

22 January 2014 1,004 1 View

Which is the best IHC Secondary detection system kit?

I'm performing IHC on mouse tissue. My primary antibodies are rat anti-mouse antibody. I would like to know which is the best secondary anti-rat HRP conjugated DAB detection system ki. There are...

14 November 2013 352 5 View

Which is the best company for ordering antibodies to immunophenotype mouse tissue by IHC ?

I am planning to immunophenotype mouse tissue that is infected with virus by Immunohistochemistry. I would like to know which company's antibodies works best for murine tissues? I have found a...

24 October 2013 5,262 25 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

Why the results when using wall thickness and when using shell conduction are different in ansys fluent?

Actually, I am running cfd simulation for a heat exchanger which has two fluids one hot and other one is cold fluid. there is a solid domain between them, which I removed and instead I have used...

01 March 2021 9,537 2 View

Can chitosan alone can act as a reducing agent for Cu(0) nanoparticle sythesis?

[Synthesizing Cu nanoparticles without using chemical reductants]

01 March 2021 8,359 1 View

What are the new 2D nanomaterials were used for Silver nanoparticles stabilization?

In the stabilization of AgNPs are vital in current research interest. However, some of the 2D nano-materials like graphene oxide, MoS2, etc... previously used to stabilize it. But still they shown...

01 March 2021 2,207 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How to check the uv-vis absorption of nanoparticle by surface plasmon resonance?

I try to check the uv-vis absorption of Indium nanoparticle. Now I am measuring in solution, can I measure it in the form of a film?

01 March 2021 930 3 View

Distribution of particles in metal matrix?

How would define the "good" and "poor" distribution of particles within the matrix. Is there a quantitative solution to assess the distribution of the particles, which then having denotation of...

28 February 2021 7,397 8 View

How can I calculate the rdf of water molecules around 'Na' ions that are closest(adsorbed) to the nanoparticle(solute)?

Hi, I want to calculate the radial distribution function for water molecules around the Na+ ions adsorbed on the surface of a spherical nanoparticle using the gromacs trajectory dynamically? For...

28 February 2021 5,650 1 View

LEDs on Vis Light photo degradation of MB water sol via N doped TiO2 in a mini flume?

Good day to all, I have no experience with light emitting diodes. I am building a glass mini flume to demonstrate the photo degradation of Methylene Blue in water running over self cleaning...

26 February 2021 4,026 5 View

Can anyone share his experience regards Smoothing in origin?

I am working on TiO2 composite material and the results of XRD have a lot of small/junk peaks and while I apply a smooth filter in Origin then the other characteristics peaks disappear so anyone...

26 February 2021 8,183 3 View