MInimisation before docking?

I am trying to do both docking and molecular dynamics simulation. Should I minimise the protein structure after adding amino acids far from active site before docking? I have taken a PDB structure...

02 November 2020 4,798 4 View

SENP1 treatment of CoImmunoprecipiteted proteins?

Dear Researcher, I am trying to imminoprecipitate (IP) Sumoylated protein. i am succesfully able to get it. now i have to carry out desumoylation of that immunoprecipiteted proteins in vitro. I...

27 February 2017 6,419 3 View

May I know somebody interested to collaborate in academic work about 'Adolescent SRH in Nepal (a quantitative study'?

27 January 2017 413 4 View

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10 January 2017 3,671 1 View

Can anyone suggest a simple calculation procedure to prepare any solution in terms of ppm ?

I am very confident and experienced enough in preparing the solutions up to ppm level when it is a SOLID, but I am confused in the case of LIQUIDS, say for example Hexadecane (hydrocarbon) has...

16 February 2015 9,202 18 View

Does use of a variable speed drive always ensure energy saving at reduced speed?

Vsd during running would result into some losses in terms of heat..my doubt is whether energy saving can be achieved at every range of reduced speed ( say @95%) considering those losses?

17 May 2014 6,855 4 View

Radiation from a porous region?

I am modelling porous medium combustion in FLUENT with a separate energy equation for the fluid and the solid zone. Since the temperature of the solid region is quite high (around 1200 K),...

11 February 2014 4,012 3 View

Do you know of a mesh based micro structure representation algorithm?

I wish to represent physical phase boundaries in a porous structure on a mesh. It seems to be quite simple to get a porous structure with the desired porosity by mere random allocation of solid...

22 January 2014 1,004 1 View

Which is the best IHC Secondary detection system kit?

I'm performing IHC on mouse tissue. My primary antibodies are rat anti-mouse antibody. I would like to know which is the best secondary anti-rat HRP conjugated DAB detection system ki. There are...

14 November 2013 352 5 View

Which is the best company for ordering antibodies to immunophenotype mouse tissue by IHC ?

I am planning to immunophenotype mouse tissue that is infected with virus by Immunohistochemistry. I would like to know which company's antibodies works best for murine tissues? I have found a...

24 October 2013 5,262 25 View

Physics: Why do we describe light by referring to its wavelength, but microwaves and radar pulses by referring to their frequency?

In physics, the description of the properties of light generally refers to its wavelength (nm), while in the range of microwaves and radio waves we refer to the frequency of a signal (e.g. kHz or...

03 March 2021 1,682 3 View

Is there any effect of different colours of light (white, red, yellow, blue etc.) on the rate of photosynthesis? If yes, why?

Light is inevitable for the process of photosynthesis reaction. Naturally sunlight plays the vital role for this process. Light may be of different colours like white, red, yellow, blue etc....

02 March 2021 7,890 2 View

How to separate water from glycerol solvent in a solvent recovery vacuum distillation column?

I am currently doing my third year design project. I have been assigned to design a glycerol recovery column in vinyl acetate monomer production. The process unit before the recovery column is an...

01 March 2021 9,525 4 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

Why is the sum of the elements in a row in a Q matrix equal to zero?

When explaining substitution models, the substitutions are expressed as Q matrix. Why is the sum of the elements in a row zero?

28 February 2021 3,864 3 View

In an eye with Tyndall, does each dot correspond to an individual cell?

When you observe the presence of Tyndall in an inflamed eye: Does each of the small floating dots correspond to an individual cell or to an aggregate of cells? Does a conventional slit lamp have...

27 February 2021 6,326 2 View

Does different dilution factors affect negatively on NH3 reading ?

I have a sample of treated water sample & asked to obtain ammonia conc. in sample using a machine with 5-25 ppm detection range. However, upon testing with different dilution factors, all...

27 February 2021 8,483 3 View

LEDs on Vis Light photo degradation of MB water sol via N doped TiO2 in a mini flume?

Good day to all, I have no experience with light emitting diodes. I am building a glass mini flume to demonstrate the photo degradation of Methylene Blue in water running over self cleaning...

26 February 2021 4,026 5 View

How can I obtain time series data by country on night-time light (brightness) ?

Hi everyone, Please, how can I obtain time series data by country on night-time light (brightness) ? I've tried, but so far all I can find are maps. I am looking for numerical data, especially in...

24 February 2021 8,625 4 View

To date, according to health authorities, 30% of the population's diseases are initiated by drinking water pollution. Do you know this problem?

The main studies are as follows: * regular and timely receipt of information about the state of the environment using automated systems (stationary and mobile); * operational analysis of the...

23 February 2021 912 5 View