Why negatively charged silver nanoparticles have shown greater anti-biofilm activity against S. aureus biofilms compared to P. aeruginosa?

16 August 2017 1 5K Report

Is it related to the charge of S. aureus biofilm which has weak negative charges due to the presence of D-alanine esters in their teichoic acids?

Both S. aureus and P. aeruginosa strains were strong biofilm formers. They had been grown in the same conditions and tested in one run with the same experiment conditions. Anti-biofilm activity of AgNPs was investigated by Calgary device- MBEC!

Henry Clemente

Our efforts using our own silver magnetic particles may have inactivated surface microbes but did not penetrate the biofilm of a process piping system. The binding of our Ag particles appears to be not charge related as much as binding to microbial surfaces and subsequently lysing or breaking the surface open

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