From experiment, I have found that the curcumin pyrazole-hydroxypropyl beta cyclodextrin inclusion complex showed more phenolic content compared to either curcumin or curcumin pyrazole prepared. Can anyone help me with possible explanation?
I would like to add that the amount of the complex was taken more for the assay based on the loading efficiency of curcumin pyrazole (as loading was not 100%, hence I took more amount of complex to maintain the equivalent amount of curcumin for the assay)
Shiva Shetty Hi. I have structurally modified curcumin (CUR) to its pyrazole (CP) form and then prepared inclusion complex (CPCD) of CP with HPBCD. CUR is a polyphenolic compound and hence checked the total phenolic content of the samples. Results demonstrated that CPCD had maximum polyphenolic content followed by CP and CUR. I need explanation for the obtained result. Thank You for your response.
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