Reason behind the absorbance peaks of beta cyclodextrin in UV-Vis spectra?

27 July 2023 1 236 Report

Please check the attached UV-Vis. spectra of Beta cyclodextrin hydrate, which exhibited peaks at 225 and 272 and a shoulder peak. Please help me write a reason behind it. I searched the literature, but it doesn't match with the published manuscripts except for one paper where they didn't explain.

Emanuel Cooper

By its structure BCD shouldn't absorb in the UV (certainly not above 200 nm). It is possible that what you see is one or more oxidized impurities. For example, if one of the 14 secondary alcohol groups gets oxidized to a ketone, this may explain your 272 nm peak (for comparison, acetone absorbs at 280 nm).

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