I performed native page electrophoresis on three single-strand DNA. The concentration of the page was 12%.

The relative molecular masses of the three DNA are10300 7884 and 7449.

The DNA 1 are modified with cholesterol, DNA 2 are modified with PC linker, and DNA 3 are modified with TAMRA.

The quality of the three DNA is all 100ng. I could only see the band of strand 3, but not the band of 1 and 2.

I can't figure out why this phenomenon occurs. Could any one give me some advice? If you can answer my question, I would be very grateful.

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