I need some papers about the DSS-colitis mice model, where aminosalicylates (as positive control) did not show an effect.
Thanks in advance
I have to prepare a formulation by dissolving sulfur in a vegetable fix oil. The sulfur is suspended in the oil and is not fully dissolved. How can I dissolve it? I really appreciate any...
06 May 2024 8,343 2 View
Generally, Tannins precipitate Alkaloids. Then, why tannins present in tea do not precipitate and neutralize the caffeine and other alkaloids present in the Tea? Thanks in advance
21 June 2022 8,514 2 View
I tested my drug, by MTT assay, on different cell lines (HeLa, Caco-2, HepG2, WI38, J774, Raw264.7) and I obtained different results in terms of cytotoxicity on these cell lines. Can someone...
01 May 2022 5,408 4 View
Which phytochemicals are destroyed (in stomach and/or small intestine) and lose their activity, when orally administered? Thanks in advance.
01 May 2022 5,598 0 View
I am planning to do Soxhlet extraction of my plant material in Ethyl acetate and Methanol. Which type of chemical constituents are at the risk of decomposition while boiling in Ethyl acetate or...
05 March 2022 5,032 6 View
I tested 1 compound and 5-ASA (as positive control) in the DSS-induced colitis mice model. Neither my compound nor 5-ASA showed anti-inflammatory activity. In fact, 5-ASA was a bit...
18 February 2022 6,375 3 View
We work on natural products to isolate some compounds that can be used as drugs. Does it also happen that while this type of research, new targets to treat that particular disease are...
13 February 2022 9,778 6 View
In in vivo, which esterase (of the animal) has the ability to break the ester bond of Gingerglycolipid A? Thanks in advance https://pubchem.ncbi.nlm.nih.gov/compound/10349562#section=2D-Structure
07 February 2022 8,125 2 View
I tested the toxicity of a drug in mice. I found increased collagen in the spleen. Can someone please share some paper to find out the reasons of this increased collagen deposition in the spleen....
06 February 2022 8,869 1 View
Can someone share some review article or link, on comparison of all the available Macrophages Cell Lines? I need to know Pros and Cons of the Macrophage Cell lines. Thanks in advance.
03 February 2022 5,628 3 View
Hello, I am currently having problems with RNA extraction. I am using mouse liver (C57BL6J), and I have extracted RNA from mouse liver before. Before this experiment, my final RNA pellets were...
11 August 2024 7,082 3 View
Can anyone share any reference that gives mouse specific CD3 antibody sequence. I have been searching for this since few days and no luck. Thank you very much
08 August 2024 9,157 4 View
How we can cite the papers from ResearchGate. I am trying to create citations for this article, Quantum Machine Learning Algorithms for Optimization Problems: Theory, Implementation, and...
08 August 2024 6,690 3 View
Hello dear colleagues, We have prepared a manuscript on NiTi-based alloys and are seeking a second opinion on our current TEM results. If you are a Ph.D. holder with experience in TEM and have...
07 August 2024 9,563 0 View
how to get links for copyrights for papers?
06 August 2024 7,410 1 View
To compare positive and negative cell populations in flow cytometry, should I compare unstained cells with antibody stained cells? Or with the isotype control? Most papers show comparison with...
06 August 2024 6,728 6 View
Hi all, I was just wondering if anyone has experience with multiplexing a mouse monoclonal primary and a rat primary. I'm trying to multiplex by incubating them in the same well but was told by a...
06 August 2024 9,710 1 View
i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...
05 August 2024 8,835 1 View
I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...
04 August 2024 9,913 7 View
I´ve been unable to find specific information about this neurotrophin in the CNS of rabbits exclusively. There is extensive info in mice, fish and rats, but in brain´s rabbit is hard to find....
04 August 2024 762 1 View