Which phytochemicals are destroyed (in stomach and/or small intestine) and lose their activity, when orally administered?
Thanks in advance.
I have to prepare a formulation by dissolving sulfur in a vegetable fix oil. The sulfur is suspended in the oil and is not fully dissolved. How can I dissolve it? I really appreciate any...
06 May 2024 8,343 2 View
Generally, Tannins precipitate Alkaloids. Then, why tannins present in tea do not precipitate and neutralize the caffeine and other alkaloids present in the Tea? Thanks in advance
21 June 2022 8,514 2 View
I tested my drug, by MTT assay, on different cell lines (HeLa, Caco-2, HepG2, WI38, J774, Raw264.7) and I obtained different results in terms of cytotoxicity on these cell lines. Can someone...
01 May 2022 5,408 4 View
I am planning to do Soxhlet extraction of my plant material in Ethyl acetate and Methanol. Which type of chemical constituents are at the risk of decomposition while boiling in Ethyl acetate or...
05 March 2022 5,032 6 View
I tested 1 compound and 5-ASA (as positive control) in the DSS-induced colitis mice model. Neither my compound nor 5-ASA showed anti-inflammatory activity. In fact, 5-ASA was a bit...
18 February 2022 6,375 3 View
We work on natural products to isolate some compounds that can be used as drugs. Does it also happen that while this type of research, new targets to treat that particular disease are...
13 February 2022 9,778 6 View
I need some papers about the DSS-colitis mice model, where aminosalicylates (as positive control) did not show an effect. Thanks in advance
10 February 2022 6,946 0 View
In in vivo, which esterase (of the animal) has the ability to break the ester bond of Gingerglycolipid A? Thanks in advance https://pubchem.ncbi.nlm.nih.gov/compound/10349562#section=2D-Structure
07 February 2022 8,125 2 View
I tested the toxicity of a drug in mice. I found increased collagen in the spleen. Can someone please share some paper to find out the reasons of this increased collagen deposition in the spleen....
06 February 2022 8,869 1 View
Can someone share some review article or link, on comparison of all the available Macrophages Cell Lines? I need to know Pros and Cons of the Macrophage Cell lines. Thanks in advance.
03 February 2022 5,628 3 View
I am working on natural remedies for de-worming in small ruminant livestocks. Part of my project involves formulation of drench-type product, which I have not much experience in. My experience is...
30 July 2024 9,806 1 View
Do You Believe VP Harris Would Show Empathy to Tech Companies in Her Administration as POTUS? I ask in light of the fact that, the ACP was not re-funded this round. So many and businesses need...
24 July 2024 4,732 3 View
This is a slice of intestinal tissue from the Chinese mitten crab (intestine in the upper right corner). I injected WSSV into this horseshoe crab. Now I want to know what these red spots next to...
18 July 2024 5,602 0 View
I have a small molecule reagent with a boc-protected amino group. Now the reaction needs to be reacted at 37°C for 30 h. Is this protection group stable?
12 July 2024 3,745 2 View
I was reading papers on plant secondary metabolites and their applications and many of the papers/books I read, have the point that plant-based medicines which are the result of application of...
08 July 2024 9,935 10 View
Hello dear researchers, I would like to know about available in silico tests that could predict the activity of ligands (small molecules) against the target protein. I have performed docking...
08 July 2024 4,724 4 View
and will i add phytochemical along with FUDR?
28 June 2024 6,254 0 View
I'm working with intestinal organoids derived from children's polyps. I use Matrigel and Human IntestiCult growing medium, and sometimes I find these structures that resemble extracellular matrix...
23 June 2024 3,938 2 View
What food do intestinal bacteria like most?ChatGPTIntestinal bacteria love fibrous foods that are prebiotic. These foods include vegetables (such as broccoli, cabbage, and brussels sprouts),...
22 June 2024 4,567 0 View
1- M.M.M. Ahmed, F.M. El Hag, F.S. Wahab, S.F. Salih (2001). Feeding strategies during dry summer for lactating desert goats in a rainfed area under tropical conditions. Small Ruminant Research 39...
18 June 2024 552 5 View