which the stage/level of clinical trails are mouse models used in？
In the U.S., drug development has pre-clinic, first, second, third stage. Which the stage that required to use mouse models to test drug?
mice are used for preclinical studies. They are not part of phase clinical trials.
https://www.alsmndalliance.org/wp-content/uploads/2015/01/Ask-The-Experts-2014-Brussels-Orla-Hardiman.pdf
Good one...
So cell line is also used in pre-clinic trails.
Which animal models do to test a drug or a treatment need to use in each clinic phase?
Is there any handout which tell us what a drug researcher should do in each clinic test and preclinic test？
Mr. Patwardhan, your handout could be not too much specific.
@ Wei Li,
See the definition of 'Clinical Trails' (https://www.nhlbi.nih.gov/studies/clinicaltrials):
"Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. These studies also may show which medical approaches work best for certain illnesses or groups of people."
At clinical trials, human beings are used, no more animals. Please see a concised description of how a drug is developed from lab to clinical trials on the website provied above.
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