What would be the ideal biomarker for evaluation of anti tnf-alpha drugs?

27 February 2014 1 7K Report

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Article Biomarkers for prediction of TNF?? blockers response in rheu...

IL-6 is induced by TNF alpha. CRP might be better. In RA, there are lots of inflammatory cytokines that are released. People typically use cytokine arrays. In terms of specific factors related to just RA, there are many things in the literature, but I don't know off hand about specific antibodies etc. maybe someone else can comment who knows the pathology of RA better than myself.

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