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I was trying many tutorials for cnn that I've found online but they are not showing good performance. But my dataset is good enough, when I try with knn or mlp in sklearn I'm getting above 98%...
01 February 2018 3,012 5 View
I was studying about ppi prediction with machine learning approach, then the latest development I've found reported 97% accuracy with DVM hereAccurate prediction of protein-protein interactions by...
11 December 2017 6,716 7 View
I was reading some papers about protein-protein interaction prediction using machine learning. I understood that using various algorithms, all the sequences are transformed into equal length...
09 October 2017 6,877 3 View
I'm looking for a tool that can give how many methyl groups, hydroxyl groups etc. are in a compound from it's SMILES, SDF or MOL2 format.
04 May 2017 9,932 5 View
My protein of interest has 3D structure available in pdb. I know about an snp that produces short isoform of that protein. How or using what tool I can produce that isoform as a pdb file?
03 April 2017 2,286 3 View
Is it possible to presume about which Salomonella species present in the sample without using molecular tools like PCR? Just from biochemical tests? If I plan to do PCR for confirming species, how...
09 October 2016 2,202 2 View
I have a list of proteins with their expression metrics. What tools can I use for predicting pathway, cluster analysis etc?
06 July 2016 4,367 2 View
For one of my experiment I need to run a program continuously for a few days. I actually do this in a local cluster. There the head node connects with the slaves with ssh and distribute the work....
04 May 2016 5,779 2 View
I've a receptor and ligand both as pdb file. With mgltools I've converted them to pdbqt. Then performed docking with autodock vina. Now I want my receptor and pdbqt generated by vina to have in a...
01 February 2015 5,001 6 View
I have dataset containing thousands of miRNAs associated with a disease collected from miRTarBase. I need some idea, about what information I can deduce/predict with in-silico/bioinformatic...
01 February 2015 8,780 3 View
Hi, I know that low molecular weight (MW) molecules generally tend to have higher mobility, while high molecular weight molecules tend to have lower mobility. However, in my experimental...
06 August 2024 1,495 2 View
After immunohistochemistry of previously fixed in PFA and EtOH and then frozen 20 μm sections of zebrafish brain, DAPI staining is very weak (right) compared to the same sections stained without...
05 August 2024 9,637 2 View
I aim to be as skeptical as possible regarding whether a pair of orthologous genes results in the same phenotype in their different but related bacterial organisms under similar environmental...
05 August 2024 6,787 4 View
I am performing ligation of the plasmid and a target gene. The steps I have taken are: 1. Double digestion of the plasmid and target gene 2. Ligation of the plasmid with the target gene 3....
05 August 2024 2,570 3 View
Brain and body mass together are positively correlated with lifespan (Hofman 1993). The duration of neural development is one of the best predictors of brain size, and conception is the best...
05 August 2024 6,247 3 View
kindly reply me. Thanking you in advance.
05 August 2024 7,727 4 View
Is it possible to conduct a molecular dynamics simulation to see the effects of a specific carbohydrate on the structure of lipids (e.g., micelle structure)? I am a beginner in this field and plan...
03 August 2024 3,371 3 View
what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...
03 August 2024 5,828 4 View
I am using a windows system, what software I should use for hydration shell analysis with molecular dynamics?
02 August 2024 3,143 4 View
Molecular docking software/ websites?
02 August 2024 8,704 7 View
