In the literature, LNCap is lymph node metastasis cell line obtained from Caucasian male and LNCaP-LN-3 is metastatic subline of LNCaP cells derived by orthotopic implantation.
I want to know the difference between two cell lines. Most of prostate cancer model mentioned in the literature is made using LNCaP cell line.
In our laboratory we have LNCaP-LN-3 cell line.
Can prostate cancer model be made using LNCAP-LN-3 cell line? and it will be the same with LNCaP?
Previously we couldn't able to develop tumor model in nude mice using LNCaP-LN-3
any insight is highly appreciated,
Regards,