Most of the time it is observed that in many manuscripts there are several typo error of topological calculation errors of calculation and partition of edges what ever the type of partitioning it is. It may be simple degree base, neighborhood degree base, temperature abase, reverse degree base or Banhatti degree etc. Also during the review of papers it amazing most of the authors do not check the mistake that leads to unauthenticated results and they also do not neither follow the definition nor theory results. How these errors and mistakes could be improved. What strategy is best to calculate them where as there mostly drugs structures are not regular and do not show regular pattern. On the other side regular graphs mostly follow a specific patter. How to improve and take error free calculations.