What is the difference between hydroxamic acid derivatives and carboxylic acid derivatives in metal chelation and chelation with metalloenzymes ?

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Marcia Moss

Irit Sagi has some data. It is not clear why some Adam metalloenzymes are not inhibitors Ted by carboxylate a but Mmps are

Check out publications by Bode. I typed in crystal structure, Mmp, and carboxylate, and got lots of references in Google.

Mohammed A. A. Abdullah

Could you send me links for these publications please ?

Dominique Liger

Hi there,

I think the attached review will be informative.