I will react PEG-NH2 with a small compound that has carboxylic acid group using a coupling agent. But I just wondering How could Purify the product?
If the size of peg is large use ultrafiltration or dialysis. Also you can add an organic solvent to precipitate the modified peg.
Ultrafiltration, Centrifugation and Dialysis are some of the choices. Much depends on the volume of the unwanted product!
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