What is the best review paper in the field of arthritis, especially covering the pathways?

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Why 3 replicates for most biological assays? Is it enough to examine the data fits normal distribution?

Just bounced on me. Before statistically analysing significant difference, shouldn't we see if data fits normal distribution first? Is 3 replicates enough to testify the hypothesis of normal...

31 July 2024 8,141 13 View

EDC carbodiimide and NHS easter 's half life among different pH?

It has been long known that EDC carbodiimide and NHS easter's half life agains hydrolysis are highly related to pH. However, very surprisingly, not yet found a paper giving a table/chart of their...

25 July 2024 8,738 0 View

How to add viscosity into a hyperelastic material such as Mooney-Rivlin rubber in LS-DYNA?

Hi, I am working on a head FE model and want to try different material types on brain. I read some papers that use Mooney-Rivlin rubber model and wondering if i can add viscosity into it. Is it...

24 July 2024 5,908 0 View

Is absolute max principal strain the same to max principal strain in HyperView?

Hi, I run an FE model on LS-DYNA solver, and concerning about the max principal strain contour result in HyperView. When I choose the result type as Strain(t)-Absolute Max Principal the contour...

19 June 2024 7,577 1 View

How to identify the correct end point from a titration curve?

Hi, I am running a titration of QAC with sodium tetraphylborate using autotitrator from Metrohm. The titrator identifies multiple end point with different ERC value. Would like to know which EP...

17 April 2024 545 1 View

Which cell line that is neither expressing iNOS Nor CD163?

Hi! I am staining iNOS and CD163 in my cells so I am looking for a minus control, expressing neither iNOS nor CD163. But the cell familiar in our lab including panc-1 and 293T seems at least...

04 April 2024 7,855 1 View

Why should we incubate ABTS stock solution for 16 hours?

ABTS stock preparation was prepared by adding ABTS and potassium persulphate.Can we use it immediately?If Cannot why?

22 December 2023 8,444 0 View

Can anyone recommend some tissue-specific gene (leaf, fruit, root) for tomato?

I am planning to design a lab practical to extract RNA from different parts of tomato, namely leaf, fruit and root, followed by expression analysis. Can anyone recommend some tissue specific...

01 November 2023 3,523 0 View

Why the Navier-Stokes equations exhibit material-frame indifference for two-dimensional flow?

According to the book written by Pope, the vorticity equations exhibit material-frame indifference when the flow is two-dimensional and the rotations of the frame are steady. But how can we judge...

15 May 2023 4,791 3 View

Why cold makes my PEG acrylate hydrogel gel faster?

Hi! I use UV and photoinitiator to gel my PEG-acrylate hydrogel. But I observe that when the temperature is lower (at night during winter), it's very easy to get pre-gelled before molding, even...

01 March 2023 9,886 1 View

Why results of ROS flurescence are negative as there was no bacteria within?

Hello. I am working on ROS production of two systems: system A is cerium oxide and hydrogen peroxide, system B is cerium oxide nanoparticle, hydrogen peroxide and potassium bromide. I did some...

04 August 2024 5,974 3 View

How to select relevant metabolites from multiple annotations ?

I am using the Polyomics Integrated Metabolomics Pipeline (PiMP) for metabolite feature analysis. After annotating my data, I have encountered cases where multiple potential metabolites are...

24 July 2024 5,789 0 View

Comparison of Methanol and ethanol treatment on collagen based scaffolds?

Kindly share a research paper that explains the effect of Methanol and ethanol treatment on collagen based scaffolds. How it increases porosity and swelling. Kindly help me find a paper. Thank you

24 July 2024 3,937 0 View

Can we fit a gaussian Fit on a LIBS Peak ?

Though much literature suggests fitting a Voigt profile on a LIBS peak, is it also possible to fit a Gaussian profile on the LIBS peak? I have 204 spectra files, and I am building a pipeline for...

23 July 2024 6,127 1 View

Fixation Problem with cancer cells?

Hello everyone, I work with polyacrylamide hydrogels, which I fictionalise with sulfo-sanpa and collagen I to then plate lung cancer cells. The problem is that I lose a significant amount of...

19 July 2024 3,906 0 View

What strains of C57 mice can induce rheumatoid arthritis?

Recently I looked up a literature《A Glucose-6-Phosphate Isomerase Peptide Induces T and BCell-Dependent Chronic Arthritis in C57BL/10 Mice Arthritis without Reactive Oxygen Species and...

09 July 2024 6,657 0 View

How to install Quantum Espresso with Intel compiler ?

Hello ! I would like to do band structure calculations of perovsikites materials with quantum espresso. For this I installed the Intel Fortran compiler. This is what I get when I run the...

08 July 2024 1,207 0 View

What is the significant difference in results obtained between biological products and their biosimilars?

I was reading the EMA's technical dossier on Nepexto where they state that: "Nepexto was considered to be as effective as Enbrel in one main study involving 517 patients with moderate to severe...

23 June 2024 9,525 1 View

Is it possible to quantify activity of the non-canonical Wnt signaling pathway via transcriptional readout genes??

Hello, From my (naive) understanding, there are several target genes of the canonical Wnt signaling pathway that serve as reliable/validated transcriptional readouts of pathway activity. These...

18 June 2024 4,699 0 View

Can anyone share a protocol for ROS assay using DCFDA dye for insect tissues?

I am trying to estimate ROS in insect tissue. Is it possible to do it using DCFDA

18 June 2024 6,954 0 View

Subhash C. Juneja

Hi Gan,

I found something might interest you. Here is enclosed a book, I downloaded from internet. Hope that helps

Hossam Shabana

I RECOMMEND THIS PAOER FOR U

PADI4 (rs2240340), PDCD1 (rs10204525), and CTLA4

(231775) gene polymorphisms and polyarticular

juvenile idiopathic arthritis