I am doing experiments with a trimer S-protein of SARS-Cov-2. I use this protein to print on a microarray plate. After this we do a neutralization assay with different kinds of serum. I want to know what the pro's and con's are of using trimers. U can also use monomers and dimers. But these don't occur in nature like this. Out of practice these ARE more specific.
https://www.nature.com/articles/s41467-021-23942-y
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649671/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410719/
Who should not get the Moderna COVID-19 vaccine?
If you have had a severe allergic reaction (anaphylaxis) or an immediate allergic reaction, even if it was not severe, to any ingredient in an mRNA COVID-19 vaccine (such as polyethylene glycol), you should not get an mRNA COVID-19 vaccine.
www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/Moderna.html
The most commonly reported side effects were pain at the injection site, tiredness, headache, muscle pain, chills, joint pain, and fever.
https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/pfizer-biontech-covid-19-vaccine-frequently-asked-questions#:~:text=The%20most%20commonly%20reported%20side,pain%2C%20and%20fever.
https://www.news-medical.net/health/What-are-Spike-Proteins.aspx#:~:text=One%20of%20the%20key%20biological,cells%20and%20cause%20infection.
Are there any long term effects of COVID-19 vaccine?
Serious side effects that could cause a long-term health problem are extremely unlikely following any vaccination, including COVID-19 vaccination. Vaccine monitoring has historically shown that side effects generally happen within six weeks of receiving a vaccine dose.
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