What are the mechanisms that affect the replicative senescence of primary somatic cell culture?

Karima Akool Al-Salihi @Karima_Al-Salihi

04 April 2014 1 3K Report

Is a shortening of the telomeres one of the limitations?

There are lots of such mechanisms. You should check the rate of gases, the serum concentration in culture medium and other factors that can affect the senescence

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Science method

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