I want to use DynabeadsMyOne C1 magnetic beads to capture sequence-specific DNA. I will attach biotynilated ss oligos to my beads as the protocol outlines to produce immobilized oligos on the beads. My question concerns the subsequent hybridization of these bead attached, gene specific probes to my genomic DNA, i.e., what hybridization buffer(s) do I use? Can you suggest or recommend what to use to do my hybridizations between my magnetic bead bound probe and my DNA genomic template? Are there standard buffers such as SSC or is there some other I should use? Also how exactly does one dry out the hybridization in a tube and for what length of time? I have done hybridization on membranes, etc. but for some reason this has me stumped! Any help or advice is greatly appreciated!