Can we use 5-10% cyclodextrin in drug release media? what are the advantages and disadvantages ?

I am interested to conduct the drug release in different release media, but i would like to know is any restriction or limitation of the concentration of other components such as...

08 September 2019 7,406 3 View

What kind of isomerism shown by steroid?

I am looking for isomerism of steroids, can you share details, books, articles, reviews discussed on steroids isomerism in details Thanks Raj Kumar

08 September 2019 3,645 3 View

What could be the reason for the sum (60-80%) of drug release and drug remain in media. is less than the total amount of drug (100%) added ?

Hi, We have formulated drug nanoparticles. interestingly, we have not found the complete release of the drugs, however, the drug release and drug left in release media is less than the amount of...

08 September 2019 1,961 5 View

How can we save interesting paper in Research gate, is it any facility to save as our own library which may useful later.?

I am everyday finding very much excellent articles related to my work in research gate, but i am unable to save them for my future requirement. is it any possibility or option to make our own...

02 March 2019 9,574 4 View

Looking for top best papers on solid lipid nanoparticles? can you please share web page or doi of papers?

Hi, I am looking for best papers on solid lipid nanoparticles which discuss science properly and interpretation of in depth results and discussion. it will helpful for me how to improve my...

02 March 2019 9,292 5 View

Reproduction permission of Figures from other's publication ?

If we took permission for reproduction before submission of journal X, but if it is rejected from Journal X, then can we use same permission of reproduction in submission of any other journal Y,...

08 September 2018 3,567 7 View

Do you have hands on experience for preparation of Fe3O4 coated with gold, silica, silver or Au, Ag, Fe3O4 coated with silica? Can you help me ?

I am working on magnetic nanoparticles coating with silica. but most of my experiments failed, Then I tried Au, Ag nanoparticles coating with silica. still facing issues. If you directly worked on...

07 August 2018 2,899 4 View

How can we get proper coating of silica or gold or silver on magnetic nanoparticles ?

I am keep on performing experiments but instead of coated nanoparticles, I am getting separate nanoparticles of silica or gold or silver when i performed experiments are well reported journal. For...

06 July 2018 9,322 3 View

What are the differences between Poloxamer 407 and Pluronic F127?

I found the chemical structure or formula of both are same even CAS No. But I want to know why both are different and why ?

05 June 2018 9,628 10 View

Can Addition of Ammonia to reaction mixture is better than addition of TEOS in preparation of Silica nanoparticles ? how and why it effect size/shape?

I am trying to prepare silica nanoparticles. I followed the literature as suggested that in all reagent in ethanol mixture added TEOS, in some other literature they added Ammonia solution to...

11 December 2017 3,408 3 View

No title

02 March 2021 3,060 3 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

What do you know about biotechnology art?

What do you know about biotechnology art?

02 March 2021 1,653 3 View

Which is the best place in the world for the plant biotechnology research?

I am searching for a good place for the Post Doc,

02 March 2021 4,053 3 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

RIA. How to measure?

When you use RIA, with a control the unknown sample with antibodies, you bare in mind the binding sites of the antibodies. However you still need to measure labelled antigen (radioactive) and not...

28 February 2021 2,133 3 View

What is the most suitable resuspension buffer for TCA/acetone precipitated protein?

I need to extract protein from fermented carbon sources for Bradford assay. Most researchers experiencing insolubility of pellet in resuspension buffer. Please assist me to select most suitable...

26 February 2021 7,129 3 View