To compare the efficacy of a new drug versus standard drug, is it necessary to have same route of administration in open label study?

More Sukainnya Buragohain's questions See All

Could you please recommend reputable researchers or research journals that delve into scram jet engines with air throttling?

The focus should be on examining kerosene fluid as the inlet fluid and placing significance on determining the specific value of carbon dioxide in this context.

19 January 2024 6,031 0 View

Are there individuals interested in proposing innovative omni directional wind turbine designs and collaborating on projects in this field?

Are there any researcher who have a desire or willingness to come up with creative and original ideas for designing wind turbines that can capture wind energy from all direction. The focus is on...

14 September 2023 409 0 View

Is it possible to devise innovative techniques that surpass the limitations imposed by the Carnot cycle?

By pushing the boundaries of conventional thermodynamic cycles, exploring new materials, and embracing sustainable technologies, I, as a researcher, can aim to enhance the efficiency of energy...

11 June 2023 5,275 4 View

Which body of water, the one in the bowl or the one in the glass, will heat up more rapidly?

In a controlled experiment, if a bowl of water is placed on a gas stove to boil and a glass is submerged within that bowl, assuming that the water temperature in both the bowl and the glass is...

11 June 2023 10,029 1 View

Is it feasible to utilize small wind turbines to power large turbines? What would be the impact on efficiency - an increase or decrease?

Is it technically viable to employ small wind turbines to generate electricity that could, in turn, power larger turbines? If such a setup were implemented, what would be the effect on overall...

11 June 2023 5,291 3 View

Could someone suggest a researcher who has prior experience working with Supercritical CO2 power cycles or in the field of gas power cycles?

I am looking for suggestions from researchers who possess previous experience or specialized knowledge in Supercritical CO2 power cycles or have conducted extensive research in the field of gas...

09 June 2023 8,539 0 View

Could someone clearly specify the thermal and mechanical loads experienced by composite materials under Hypersonic conditions?

Hypersonic vehicles, which travel at speeds greater than Mach 5, experience extreme thermal and mechanical loads during flight. The objective of this research is to investigate the behavior of...

08 June 2023 8,727 1 View

Can it be stated that severe boundary layer separation results in increased turbulence?

Can it be posited that the presence of a severe boundary layer separation, characterized by the detachment of the fluid flow from a solid surface, serves as a significant contributing factor to...

03 June 2023 7,334 23 View

What factors govern the formation and dynamics of turbulent flow, and how can we better understand and predict its behavior?

This question delves into the fundamental nature of turbulence, a ubiquitous phenomenon in fluid dynamics that is characterized by chaotic and unpredictable fluid motion. Exploring the mechanisms...

01 June 2023 334 6 View

Can anybody tell me a topic of research for an aerodynamic related area !?

I'm looking for a problem to take up as an objective to research on it.

04 May 2023 9,686 4 View

Is changing the medium during the experiment overestimate the results?

I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...

07 August 2024 2,283 2 View

For an in-vitro drug release study, what molecular weight cut-off (MWCO) dialysis bag is required for a 117 kDa protein?

kindly reply me. Thanking you in advance.

05 August 2024 7,727 4 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View

Research on politics administration relation can conduct based on case study method?

01 August 2024 9,557 1 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View

What is the optimal financial policy to be followed at the present time?

I believe that we must resort to a more conservative financial policy, that is, less expenditure on the current side than it is at the present time, in addition to high coordination with monetary...

24 July 2024 7,262 2 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

Can somebody share a diversity and inclusion questionnaire for the business context or military context?

Dear All, Can somebody share a diversity and inclusion questionnaire for the business context or military context. Thank you Anuradha

22 July 2024 1,320 4 View

What is the broad objective in determining the knowledge of healthcare workers in pre-operative fluid management?

21 July 2024 5,133 0 View

Donna Lisi

This could lead to bias as in this study comparing IV to po corticosteroid use In asthma where more severe patients were given intravenous therapy.

Article Observational Study of Intravenous versus Oral Corticosteroi...

This observational study on the other hand, compared IV to po clarithromycin in community acquire pneumonia and it’s investigators felt that adequate propensity scoring eliminated treatment bias.

Article Oral versus intravenous clarithromycin in moderate to severe...

Abdelkader Mohamed Elsayed

Nice Contribution Frank T. Edelmann