Strange big morphology in THP-1 culture?

21 September 2024 1 1K Report

I recently found suspicious big cells in my THP-1 cell culture. It seems like some cells but much larger than the others. What could it be? Is it contamination or cell morphology changes?

Ellen A G Chernoff

THP-1 cells can form Multinucleated Giant Cells. Some strains form more than others:

http://www.journal.med.tohoku.ac.jp/1862/TJ1862_04.pdf

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