Are there "non-toxic" ionic liquids that increase the solubility of paracetamol, ibuprofeno, etc. with respect to water, at 25-40 ºC but in a "safe for health" manner?
The solubilities of paracetamol and ibuprofen were determined in two different ionic liquids at temperatures of 298.15 K, 308.15 K, 318.15 K, 328.15 K, and 338.15 K. The ionic liquids selected were 1-butyl-3-methylimidazolium hexafluorophosphate [BMIM][PF6] and 1-hexyl-3-methylimidazolium hexafluorophosphate [HMIM][PF6]. show article "Solubilities of Pharmaceutical Compounds in Ionic Liquids".
Dear Mostefa Boumediene, thank you very much for your quick response. Could you send me the full-text you are talking about (and anyone similar). I can't find it on any network! Will there be an error?
Smith, K. B., Bridson, R. H., & Leeke, G. A. (2011). Solubilities of pharmaceutical compounds in ionic liquids. Journal of Chemical & Engineering Data, 56(5), 2039-2043.