I would like to differentiate mouse splenic B cells to plasma B cells, but I cannot find a clear protocol. Does anyone have this for me or can give me tips?

Normally, I isolate resting splenic B cells using CD43 MACS beads. Are this the B cells you need to differentiate into plasma B cells?

And I read somewhere that it is possible to do this by culturing splenic B cells with LPS for a couple of days, following incubation with anti-CD40 for 48h. Does this sound familiar? And what concentrations should I use?

Thanks in advance for any advice!