It is hard to imagine that dried PRP will have much use. I cannot answer how long the various repair factors will remain active after drying, but the real issue is that PRP requires good quality unactivated platelets.

Platelets live for approx 8-10 days after they have been activated and continue to make the factors till their energy stores are depleted. Platelets release about 90% of their initial stores immediately on activation so the principle is that you should get them to where you want them before activating them. This could be within a fibrin clot when used in dentistry. However it is almost certain that the immediately released growth factors do not remain active for very long and the real effect is from the continued production of new growth factors over the next few days

It is doubtful that Platelet-Rich Plasma Powder Preparation is of any clinical use.

PRP powder opens up new possibilities for PRP research however, it is mandatory to have a clear basic science study followed by clinical application. It is important to show the different concentrations of GFs and the inter individual differences between the GFs and interleukin.

I cannot help but feel that the idea/hope that looking at GF extracts of PRP is a distraction. It is no longer PRP since one has lost the biological functionality of platelets as a regulating producer and releaser of GFs over a period of time, and to see GFs as operating in isolation misunderstands the biological process and transposes a complex interaction of multiple processes into a single mechanism.

GFs merely bind to intracellular receptors that switch on and off cellular functions. They have a limited life and limited binding affinity, and the process requires a drip feed of new GFs to continue the tissue repair processes they help to initiate.

Sure the study of freeze-dried GFs is a useful tool to help understand how they work, but in the clinical field we have a magnificent process within Platelet functionality, and it is simple and cheap to harvest autologous fresh and fully functional platelets that can be used clinically.

All one needs are citrate blood tubes that cost pennies and a swing-basket centrifuge for $1000 from China that has a gradual brake and can spin down to 100g, and large quantities can be produced with ease. One doesn't need these ridiculously expensive kits producing only 10-20ml of PRP (and PPP that contains GFs from damaged/activated platelets, but no actual platelets).

At the moment companies make unsubstantiated claims on how THEIR system is better than anybody else's. My research has shown that at 150g for 10 mins all the RBCs and over 99% of the granulocytes are removed, while keeping almost all the platelets within the plasma supernatant. Surely the place to be doing the research is how to improve on the scientific understanding of what is happening within the centrifuge process