Hello!
I inject 1 mg/ml Collagen + matrigel mixture in one channel of my device and 2mg/ml collagen in the adjacent channel. Two channels are separated by microposts. I somehow see hydrogel retraction around the microposts or in collagen+matrigel region after 1-3 days of injection.
Have you encountered something like this and how should I solve it?
Parisa Taklifi
Hydrogel peeling and retraction in microfluidic devices can be attributed to various factors, including improper bonding between the hydrogel and the substrate, mechanical stress, and differences in material properties between adjacent channels. Here are some strategies to prevent hydrogel peeling and retraction:
By implementing these strategies and optimizing the experimental parameters, you can minimize hydrogel peeling and retraction in microfluidic devices and improve the reliability and reproducibility of your experiments.
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