What are the parameters most required? For liver is there anything more than AP, ALT and AST? And for kidney anything more than Creatinine and Uric acid?
To assess kidney function you may want to check:
>Urine:
-Osmolality (or specific gravity, however this parameter is not always a good estimate of urine osmolality)
-Creatinine
-pH
>Blood (serum)
-perform kidney panel which usually includes creatinine, BUN (Blood Urea Nitrogen), Albumin, Total Protein, Phosphorus, Potassium, sodium, Calcium and Chloride;
Analyzing results it's crucial to refer to reference intervals assessed for a given strain of mice/ age/ gender. Apart from literature data it's useful to establish your own reference values, based on results of healthy individuals that you keep as a control group in your lab/facility.
Hope that helps!
Best,
Magdalena
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