Almost all IBD guidelines refer mesalazine as "gold" or standard treatment for mild to moderate cases (Mayo classification).  Nearly 15-20% of the patient series need to add a local-topical steroid as a add on therapy in order to maintain control-remission.

Thank you,

But the route of dose administration is intravenous. it is very difficult to use mesalazine as it is available in tablet form only.

The effect of mesalazine can be obtained only through topical route. systemic effects are only responsible for side effects. if you need an intravenous only drug, the optimal drug would be tnf antagnosists e.g. infliximab which also also rapid onset action. steroid would not be the first choice choice as long term mucosal healing effect  and long term clinical efficacy is quesitonable with this drug.