What could be the quantitative amount of H2O2/g of protein present inside the cancer cell?
It is interesting, according to one literature, Hydrogen peroxide (H2O2) is an important signaling molecule in cancer cells. However, the significant secretion of H2O2 by cancer cells have been rarely observed:
there is some answers in the paper:
Article Calculated Cell-Specific Intracellular Hydrogen Peroxide Con...
Generally, cancer cells undergo oxidative stress, and the intracellular concentration of reactive species of oxygen, including the most stable hydrogen peroxide depends on redox cycling. H2O2 generation is a dynamic process and it can’t be measured as you suppose. You can read this recent mini-review, in which you can find my answers to you questions and references that could help you better understand the role of H202 and concomitant electrophiles in cancer.
Article Reactive Chemicals and Electrophilic Stress in Cancer: A Minireview
The amount of H2O2 present inside the cancer cell can be determined by the following protocol in the article. Good luck!
Article Tumor cells have decreased ability to metabolize H2O2: Impli...
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