I have a series of RNA-seq datasets that their average spot length is about 90bp. (don't include small RNA reads like mature miRNAs). I'd like to do "Gene" and "precursor miRNAs" expression analysis on them.
my question:
Is there any correlation between mature miRNAs and their precursors?
and could the expression of the precursor miRNAs be correlated to the expression of the mature miRNA?
Thanks in advance
Dear Ali Reza Eivazi,
I have provided the answer to your question in the form of a research description and I hope you will get your answer.
My master's thesis was on the expression of the mir-206 gene, a precursor to miRNA 206. This miRNA can increase the myogenesis of skeletal muscle in poultry and humans by silencing the MSTN gene.
During this evaluation, the expression of precursor gene was increased, which based on the live weight measured before the slaughter of the studied poultry, indicated the effect of precursor on mature miRNA and consequently increased skeletal muscle volume and myogenesis.
Dear Mehrdad Mohebi Shahpour Abadi
Thank you so much for answering.
I think it should be so, but I have not seen any paper related to this correlation.
Did you publish any papers or results about this correlation?
Ali Reza Eivazi
I'm writing the full article, but part of the research is in the form of a conference paper on my page.
Conference Paper Evaluation of mir-206 gene expression in the liver of broile...
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- Biological Science
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- RNA
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