Can we use 5-10% cyclodextrin in drug release media? what are the advantages and disadvantages ?

I am interested to conduct the drug release in different release media, but i would like to know is any restriction or limitation of the concentration of other components such as...

08 September 2019 7,406 3 View

What kind of isomerism shown by steroid?

I am looking for isomerism of steroids, can you share details, books, articles, reviews discussed on steroids isomerism in details Thanks Raj Kumar

08 September 2019 3,645 3 View

What could be the reason for the sum (60-80%) of drug release and drug remain in media. is less than the total amount of drug (100%) added ?

Hi, We have formulated drug nanoparticles. interestingly, we have not found the complete release of the drugs, however, the drug release and drug left in release media is less than the amount of...

08 September 2019 1,961 5 View

How can we save interesting paper in Research gate, is it any facility to save as our own library which may useful later.?

I am everyday finding very much excellent articles related to my work in research gate, but i am unable to save them for my future requirement. is it any possibility or option to make our own...

02 March 2019 9,574 4 View

Looking for top best papers on solid lipid nanoparticles? can you please share web page or doi of papers?

Hi, I am looking for best papers on solid lipid nanoparticles which discuss science properly and interpretation of in depth results and discussion. it will helpful for me how to improve my...

02 March 2019 9,292 5 View

Reproduction permission of Figures from other's publication ?

If we took permission for reproduction before submission of journal X, but if it is rejected from Journal X, then can we use same permission of reproduction in submission of any other journal Y,...

08 September 2018 3,567 7 View

Do you have hands on experience for preparation of Fe3O4 coated with gold, silica, silver or Au, Ag, Fe3O4 coated with silica? Can you help me ?

I am working on magnetic nanoparticles coating with silica. but most of my experiments failed, Then I tried Au, Ag nanoparticles coating with silica. still facing issues. If you directly worked on...

07 August 2018 2,899 4 View

How can we get proper coating of silica or gold or silver on magnetic nanoparticles ?

I am keep on performing experiments but instead of coated nanoparticles, I am getting separate nanoparticles of silica or gold or silver when i performed experiments are well reported journal. For...

06 July 2018 9,322 3 View

What are the differences between Poloxamer 407 and Pluronic F127?

I found the chemical structure or formula of both are same even CAS No. But I want to know why both are different and why ?

05 June 2018 9,628 10 View

Can Addition of Ammonia to reaction mixture is better than addition of TEOS in preparation of Silica nanoparticles ? how and why it effect size/shape?

I am trying to prepare silica nanoparticles. I followed the literature as suggested that in all reagent in ethanol mixture added TEOS, in some other literature they added Ammonia solution to...

11 December 2017 3,408 3 View

Resistor definition in Piezoelectric bimorph with ANSYS workbench

Hello, good day! I am trying to simulate similar bimorph piezoelectric harvester with below commands. However, the output power doesn't change with resistor value. Please help to find the reason. ET,10,CIRCU94,0 !SET UP RESISTOR R,1,100000 !RESISTANCE VALUE TYPE,10 !SET ELEMENT TYPE E,1,2 !CREATE RESISTOR BETWEEN NODES 1 AND 2 Thanks in advance Regards,

02 March 2021 0 0 View

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02 March 2021 3,060 3 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

How to define tie constraint between rigid body and another part in dynamic explicit model of Abaqus?

Hi dear researchers I connected a rigid body into the part of my structure by tie constraint and then I added displacement to rigid body, in static general step every thing is fine and these two...

28 February 2021 3,442 2 View

No title

28 February 2021 9,936 2 View

When is it unnecessary to change organisational culture?

As a former management practitioner, I recall a generally accepted view that changing organisational culture is difficult, so you should only attempt it if the organisational change that you are...

27 February 2021 2,595 8 View

Does RNAiMAX transfection reagent work in serum free medium?

I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...

26 February 2021 10,041 3 View

What is the best surface to culture cells isolated from a skin biopsy?

Hello, recently I am having some difficulties with maintaining the cell culture of primary cells isolated from a skin biopsy (normal and malignant). The coating of culture plates with Matrigel (a...

26 February 2021 6,151 2 View

Unknown debris sheets observed in cell culture flasks?

Hi, We culture neural progenitor cells in T175 culture flasks coated with PLO-Laminin. We have successfully grown these cells with our protocol for months. Recently, we observed large sheets...

25 February 2021 3,443 4 View

Has anyone experienced changes in growth for cell culture when purchasing media from different companies?

I recently switched the company where we buy our DMEM/F12 and i have noticed a signficant change in growth for my human olfactory neurosphere cell lines

24 February 2021 2,268 3 View