Does the 10 mg labeling on Nab-Paclitaxel (HY-P99974, MCE) indicate the powder weight or pure paclitaxel? Seeking advice from those who've used it for animal studies!
Yes. The product specification refers only to the active content of paclitaxel; the actual amount of human serum albumin may vary between batches. In our product, the ratio of paclitaxel to human serum albumin is approximately 1:9 (ranging from 1:7 to 1:11). Specifically, the 100 mg refers to the active ingredient paclitaxel. For small-vial Nab-Paclitaxel products, each vial contains 100 mg of paclitaxel and approximately 813 mg of human serum albumin. https://www.researchgate.net/post/In_Nab-Paclitaxel_does_the_product_specification_indicate_the_amount_of_active_paclitaxel The answer to this question comes from MedChemExpress (MCE) Technical Support.
The 10 mg labeling on Nab-Paclitaxel (HY-P99974, MCE) typically refers to the total weight of the lyophilized powder, which includes paclitaxel bound to albumin nanoparticles—not just pure paclitaxel. For accurate dosing in animal studies, refer to the specific paclitaxel content provided in the product datasheet or certificate of analysis.
Nab-paclitaxel consists of a lyophilized powder, which is reconstituted with 20 mL 0.9% sodium chloride solution before intravenous infusion. Each single-use vial contains 100 mg of paclitaxel and approximately 900 mg of human albumin.