Hi Bill, many thanks for your offer. At least we want to co-immunoprecipitate a TRAF6 associated kinase … is it possible to couple these single stranded aptamers to our magnetic beads? Do we need a spacer which might influence the functionality of the aptamer? What about costs for this development?
We can certainly couple to bead either with an amine-modified aptamer (probably the best way) with epoxy or COOH beads or with biotin-aptamer. You can email me directly at [email protected]. I hope we can help!