How Relativistic effects is one reason for lanthanide contraction?

The Lanthanide contraction which is the decrease in ionic radii of the elements in the lanthanide series from atomic number 57, lanthanum, to 71, lutetium, is due to poor shielding of the 4f...

01 March 2021 2,272 4 View

What is the best way to calculate sample size for a multivariate regression model for adequate power?

GPower is only equipped to deal with calculations of bivariate regressions and needs SD s for both predictor samples. However, if one has a multiple regression with more than 2 outcome variables...

12 February 2021 6,911 3 View

How Marcus free energy, reorganization energy is related to thermal effect for electron transfer state?

The molecules separation medium is associated to medium permittivity of Frenkel effect and naturally diverse environmental temperature may influence the electron transfer process in organic...

02 February 2021 5,168 3 View

Alpha synuclein lack structurw (i.e some of the helix part goes into turn ), any cause behind this?

I am trying to simulate alpha synuclein (1xq8.pdb) in GROMACS using GROMOS53a6 ff. I have run it for 200 ns. At the end of simulation alpha helix protein losses its helical structure. I am not...

31 January 2021 4,285 3 View

In which laboratory of India 13C NMRanalysis of solid samples could be performed?

I need to analyse some solid samples (soils) for 13C NMR. Is there anyone who can help me out? The contribution of the contributor would be properly credited during any sorts of publication....

07 January 2021 2,016 4 View

Why the presence of surface active compound repress the mass spectra of other compound? If the sample is itself surface active, then self repression?

I am assuming the resulting insertion/agglomeration in the presence of a surfactant or the agglomeration of surfactant may reduce the rate of ionization. The mobility of the ion may also be...

07 January 2021 987 5 View

What are the mental health insurance policies in different countries?

Post Covid 19 the scenario in India has changed and some of the private insurance companies are providing coverages for mental disorders. So My question is what mental disorders are covered in...

04 January 2021 6,474 10 View

In a microgel-DTPA suspension (in water), what can be added as a counter to TMEDA to adjust its pH to 6?

I have added a little extra TMEDA to the microgel-DTPA suspension and has reduced its pH. How can I bring it to pH 6?

04 January 2021 6,743 1 View

Does posting articles to Research gate gives any edge or credit to a student in Phd application?

Does posting articles to Research gate gives any edge or credit to a student in Phd application?

07 December 2020 4,001 3 View

Where to get free cancer patient demographic data?

Is there any freely available global repository to get cancer patients' demographic data? #cancer #cancer_research

06 December 2020 5,469 2 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

What is the exact mechanism of the antimicrobial effect of local anesthetics?

The antimicrobial effect of local anesthetics has been known for more than 50 years, but it still seems to have an unclear mechanism of action. which bacteria? which concentration? etc etc. ....

27 February 2021 4,450 2 View

I want to performe MALDI-TOF MS for bacterial identification, I would appreciate it if anyone can tell me the matrix solution preparation protocol ?

based on what I've studied on multiple papers, for peptide and protein identification Alpha-cyano-4-hydroxycinnamic acid (CHCA) is an appropriate matrix to use, I also know that the CHCA powder...

26 February 2021 6,799 3 View

Is IMPACT FACTOR justified in case of Taxonomy?

There is huge pressure of getting good impact factor on scholars now a days. On the other hand Taxonomy is a very dry subject and the concerned papers can only get citation in same group of organism.

26 February 2021 5,851 1 View

Uncertianiny in using dry or wet basis in mixing a sediment with fuel oil?

Hello I'm currently working on a topic related to studying the anaerobic biodegradation of TPH in marine sediments. In this work, sediment should be mixed with fuel oil to a concentration of 20 g...

24 February 2021 9,839 3 View

Standard curve shifting over time. How do I stabilise the ELISA?

24 February 2021 1,365 3 View

Advice on growing lactobacillus species in the lab?

Hello everyone, For part of my PhD project, I'm hoping to grow some lactobacillus species in the lab so that I can create standard curves for a qPCR quantification of a faecal sample. However, I...

24 February 2021 3,157 6 View

How can I selectively dry etch Ti on a polymer substrate?

24 February 2021 5,378 1 View

How to best wash a 96-well plate containing microplastic?

I am planning my protocol for my dissertation for an experiment quantifying bacterial (E. coli) biofilm formation on micro-plastic (5mm discs of polyethylene bags) by conducting a crystal violet...

23 February 2021 7,868 2 View