how to induce jurkaT cell dysfunction?

10 January 2020 1 1K Report

1. Can JurkaT cells be used to replace primary human T lymphocytes for the study of T cell dysfunction?

2. How to induce JurkaT cells dysfunction or exhausted?

3. Can JurkaT cells differentiate into different subtypes(Th1,Th2),like the CD4+ T cell?

Treat it with dexamethasone but you have to optimize the concentration so that Jurkat cells will not be totally depleted.

https://pubmed.ncbi.nlm.nih.gov/16406604/

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