It isnt dissolving in any solvent, i have tried water, methanol, DMSO and ethanol and also tried changing the temperature and pH. Can anyone suggest a suitable solvent or a methodology?
What kind of tablet are you using? Sotalol HCl should dissolve in water up to a concentration of about 5g/l.
Is the tablet decomposing or does the tablet keep its form? Some tablets (for example tablets with a modefied drug releas) are made to keep their shape.