I just got an ancestry profile from a DNA sample and am wondering how reliable the results are. If test analyses were repeated, how consistent would haplogroup findings typically be? Does the rarity of the particular grouping typically make results less reliable?
It is a function of the quality of the sequencing, the pylotree representing the haplotypes (more complex vs simplier) and the quality of the algorthm that classifies key polymorphisms.
For example- HaploGrep is fairly well cited algorithm. I found a haplogroup classification table online and it indicated that
"a Haplogroup determined using Affymetrix Genome-Wide Human SNP Array 6.0 data and HaploGrep (Kloss-Brandstätter et al. 2011) based on Phylotree built 11 (van Oven and Kayser 2009) b n. d., not defined, i.e. all individuals with a HaploGrep’s quality
- Badges
- Science topic
- Similar topics
- Biological Science
- Molecular Biology
- Biomolecules
- Nucleic Acids
- DNA