Brain cells process thoughts (energy) of different class and quality in an area-specific manner. The NaAF-driven Na-pump is the voltage generator across brain cell plasma membrane, hence is the earliest electromagnetic-boundary (or gate) that the area-specific thought signals (electromagnetic) encounter. The human body is essentially a bundle of electromagnetic energy that owes its very existence to the presence of abundant inorganic ions (~ 300 mM) distributed differently between the cells and circulating blood where the semipermeable plasma membranes having Na, K-ATPase pumps act as the differential ion barrier. Function of the dual-channel Na-pump (Na, K-ATPase) fully depends on a ubiquitous cytosolic regulator, NaAF of 170 k Da mass maintaining the ion gradient (or electromagnetic potential) for carrying out numerous interlinked processes. Energy and information continually flows through this intricate intra- and inter-cellular network in order to maintain the mind-body functions supervised by the brain.
NaAF being the first molecular driver of the Na, K-ATPase pump, it is likely to be the natural mediator of transcendental Will-power (electromagnetic thought-signals). Different areas of the brain containing different αβ-isoforms of the Na, K-ATPase have differential affinities towards Na, K, Ca and ATP. Hence, the nature and intensity of the area-specific thought-signals will be handled with different efficacy during transmission of the signal. Following depolarization those Na-pumps at the synaptic junction acting as provisional Ca-pumps (in altered states) to drive out excess Ca (> 10 µM), will also show differential activities towards Ca based on isoform (αβ)-nature, affecting time for repolarization and the signal flow.
Expectedly, the ubiquitous NaAF maintains its own intracellular level via gene-expression (on demand basis) in all cell types. In brain the sublime Will-power (opener of thought signal) may additionally influence the cell NaAF level by microRNAs at the level of translation (from mRNA level). This is based on recent evidences on heart-pump related signaling proteins in cardiac hypertrophy (Rooiz et al PNAS 105, 13027–13032, 2008) and heart failure.
I want to add few more lines towards further clarification of Will-Power generating the electromagnetic thought signals in area-specific brain function. Will-power is exerted by transcendental ego or "I", or the decision maker for the execution of course of action to be taken. Hence, the outcome will rely on the individual's (egoistic) biases, thus choosing different brain areas in different persons (in response to the same question) for the kind of thought signals.
So, "I" or ego is the controller of all bio-molecular controllers in a person's body. Therefore, ego can control the most powerful regulator, NaAF of cellular homeostasis in an individual, possibly via microRNA as mentioned earlier.
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