How long does an Aminoacyl-tRNA-Synthetase live? How often is it reproduced?

More Hanna Schumacher's questions See All

What are overall assumptions for comparing two enzymes of the same class consisting of more or less different amino acids?

I do research on genetic code and aminoacyl-tRNA-synthetase (aaRS) evolution. An aaRS consists eihter of 18, 19 or 20 amino acids. Are there biological rules or findings that allow the assumption...

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Is there a similar approach on genetic code evolution?

Is there anything similar to a simulation that starts with a random genetic code and some genes that are translated into aaRS proteins which change the genetic code because the new aaRS aren't the...

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Which simulations of genetic code evolution do exist?

Are there simulations that... - simulate changes in the tRNA pool? - simulate flexizymes? - simulate aaRS? I did a lot of research but didn't find practical approachs on the role of these three...

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Does a flexizyme or sth. similar exist that can charge a tRNA with two different amino acids?

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Ribozym, flexizym, mRNA, tRNA. What is missing for protein biosynthesis?

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Karthik Krishnamurthy

I think it depends on the species which you are studying. Please check the attached paper

Andreas Stadler

Hi,

proteins are usually stable up to 1 or 2 days in cells, RNA is far less stable and degrades within some minutes or up to some hours. Protein and RNS stability depends on the species. Higher species have much longer protein and RNA life time.

See the following webpage, it has some interesting figures

http://book.bionumbers.org/how-fast-do-rnas-and-proteins-degrade/

Viele Grüsse,

Andreas