Hanna Schumacher

7 Questions 6 Answers 0 Followers

Questions related from Hanna Schumacher

What are overall assumptions for comparing two enzymes of the same class consisting of more or less different amino acids?

I do research on genetic code and aminoacyl-tRNA-synthetase (aaRS) evolution. An aaRS consists eihter of 18, 19 or 20 amino acids. Are there biological rules or findings that allow the assumption...

02 February 2019 1,016 8 View

Is there a similar approach on genetic code evolution?

Is there anything similar to a simulation that starts with a random genetic code and some genes that are translated into aaRS proteins which change the genetic code because the new aaRS aren't the...

01 January 2019 6,676 1 View

Which simulations of genetic code evolution do exist?

Are there simulations that... - simulate changes in the tRNA pool? - simulate flexizymes? - simulate aaRS? I did a lot of research but didn't find practical approachs on the role of these three...

01 January 2019 2,305 1 View

How long does an Aminoacyl-tRNA-Synthetase live? How often is it reproduced?

For my current project I do a lot of research about aaRS but didn't find answers to these questions yet. I am happy about any information about the lifecycle of these enzymes.

11 November 2018 5,150 2 View

Does a flexizyme or sth. similar exist that can charge a tRNA with two different amino acids?

Is there any aaRS like construct that charges either... ...one tRNA with one out of two amino acids or ...two tRNAs with one amino acid each but not the same amino acid. Further more there is...

11 November 2018 6,059 0 View

Ribozym, flexizym, mRNA, tRNA. What is missing for protein biosynthesis?

Protein biosynthesis in an RNA world could have had the following components: ribozymes instead of ribosomes, flexizymes instead of aminoacyl-tRNA-synthetases, mRNAs, tRNAs, other kinds of RNAs....

01 January 1970 4,848 1 View

Which research approaches consider the influence of protein biosynthesis products on genetic code evolution?

I've read a lot of research but didn't really find theories that include the influence of the produced proteins on the evolution of the process in general and the genetic code in particular. I'd...

01 January 1970 6,401 2 View