Has anybody looked at the allred score of MCF-7 and T47D cell lines? I understand that one is PR positive and the other negative. What is the status of expression of ER relatively in these two cell lines?
Both cell lines are ER+, with MCF7 having higher expression. There are quite a few studies that have looked at gene expression in breast cancer cell line panel. Check out paper by R Neve and JW Gray 2006 Cancer cell and other more recent JW Gray paper.