How can I do intracerebral administration in suckling mice?

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Liz Unger

This paper uses a 60um pulled glass pipette to inject into E11.5 mouse brain, and they survive just fine. (Including pictures, see Fig 1B)

Article Efficient Gene Transfer into the Embryonic Mouse Brain Using...

Daniela Noaín

Check this paper from Avale and colleagues:

Mol Psychiatry. 2004 Jul;9(7):718-26.

The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder.

Avale ME1, Falzone TL, Gelman DM, Low MJ, Grandy DK, Rubinstein M.

They did intracerebral administration of newborm mice.

I hope it helps!

best

Daniela