How can I avoid high mortality of rotenone-induced PD?

10 October 2014 1 10K Report

I used 1.5mg/kg dissolved in DMSO/PEG 1:1 and I have high mortality intraperitoneal injection.

thanks, But my problem is that i don't have sterotaxial instrument to inject the rats intracranial, as i know that will avoid the mortality and cardiac problems.

if i want it to be IP or IV. wha i have to do and the best dose with concentrations.

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