HEK293 and HEK293T cell lines?

12 December 2017 1 3K Report

What is the difference between HEK293 and HEK293T cells? HEK293T is also written as 293T cells?

Thanks

Regards

HEK293 cells are the parental line for 293T. The "T" means that it expresses the Large T antigen which is important for replicating plasmids containing an SV40 origin of replication to high copy number in the transfected cell.

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