Hi everyone..how to calculate sample size for comparative study?

I want to compare efficacy of drug A with drug A plus B in prevention of a disease by giving one group drug A while giving drug A and B to other group. The problem is I have previous data on drug...

01 October 2020 1,724 3 View

How to manage the disposal of 1000 ppm Hydrogen peroxide gas after fumigation?

I use 1000ppm Hydrogen peroxide gas (HPV) to do disinfection( open loop) of biopharmaceutical isolator. At that concentration, it's very harmful so could anyone please recommend how to manage with...

22 July 2020 2,157 3 View

Which is the best assay to check the maximum non-toxic dose of a new compound, to be tested for antiviral testing?

Most of the papers on antiviral studies use MTT assay to check the cytotoxic concentration of any new molecule (synthetic or natural). This assay gives an idea about the maximum non-toxic dose of...

10 September 2018 3,740 2 View

How can I quantify/find a concentration of DNA released from apoptosis and released from NET (neutrophil extracellular trap) formation at same time?

23 February 2015 7,781 3 View

How to eliminate Steady state error from Reinforcement learning genetic algorithm code?

The following code (see 1st 2 images attached) is used to produce PID controller values that are designed to control the system (G). The code finds the PID controller values (noted as k) by using...

28 February 2021 6,560 14 View

Is anyone familiar with the cyclic compressive fatigue testing (BS EN 12697 - 25) ?

I would like to get more information on the cyclic compressive fatigue testing (BS EN 12697 - 25) which is typically done for bituminous material in pavement design. Any one can advise on the...

28 February 2021 2,004 3 View

Can we recognize signs of the "volatility clustering" property of a time series in its time domain plot?

My purpose is to recognize the volatility clustering property without statistical tests such as The Lagrange Multiplier (LM) test.

24 February 2021 4,150 3 View

How to constrain genetic algorithm input u?

My real system (buck converter) can only take an input of 0 to 1 (duty ratio) and I need to constrain the system so the controller action keeps within this bounds. How can I do this? The code for...

22 February 2021 2,125 3 View

How we can measure Kemp % in wool without using of benzene?

Would you please let me to know about the methods for measurement of medullation and Kemp % on animal? My problem is that the wool sampling and sending to laboratory is not possible. So I would...

21 February 2021 7,260 4 View

Which statistical test to use for comparison of different groups in a categorization?

I am doing a study on how programmers with different levels of expertise choose class names. A description was provided to the participants together with a list of possible class names for the...

21 February 2021 3,662 4 View

Statistical Tests for Quantitative Study?

Hello Everyone, I have one population, sample size 200. and needed to find the correlation between Variable A and B. Also, which T-test should I choose for hypothesis testing Please advise...

21 February 2021 7,591 4 View

Methodological confusions regarding deductive and inductive reasoning, hypothesis and theory test?

Hi Colleagues- What do you think about the following methodological issues: 1. Is it methodologically wrong to formulate quantitative research questionnaire based on inductive reasoning? 2. Is it...

21 February 2021 4,634 6 View

Choice of Ab for Co-IP: Does an anti-(tag) antibody (such as anti-flag/ anti-myc) a must if I am using co-transfected cells for Co-IP?

Hi guys, I am trying to detect the binding of 2 proteins by Co-immunoprecipitation. However, the choice of antibody is confusing me. I tried probing the endogenous protein right away but the...

16 February 2021 9,050 5 View

Which statistical test is best to seperate out treatment effects meta-analysis?

I am doing a meta-analysis and am looking for some guidance on which statistical test will help me do the following. I want to understand the effect size a treatment has on a population. There...

16 February 2021 8,033 3 View