is there any ways that i can find genome similarity of an organism without whole genome sequencing ,like using maths formulas or experimental progress ?
16S rRNA Gene for Bacteria: For bacterial organisms, sequencing the 16S rRNA gene can provide insights into genetic similarity. This gene is highly conserved among bacteria but contains variable regions that can be used to differentiate species.
COI Gene for Animals: In animals, the cytochrome c oxidase I (COI) gene is commonly used for DNA barcoding and can be used to estimate genetic similarity.
Yes we can calculate similarity based on multilocus sequence analysis (MLSA) or by average nucleotide identity (ANI) based partial genome sequences or selected conserved gene sequences like 16S rRNA for prokaryotes.