We have prepared molecularly imprinted polymeric nanoparticles by polymerizing functional monomers along with a template. After synthesis, the template is removed by 5 days of dialysis in milliQ water, (acetic acid is added on the second day) to facilitate the template removal.
If the organic solvent is miscible with water, it will equilibrate across the dialysis membrane and interact with substances inside the bag.
Dear all, if you have clear and homogeneous solution, then you may expect interactions. Solubility means there is such mutual interactions. Both water and acetic acid are polars, that's why they are soluble, the same would be with residual monomers, which are automatically polar since they are soluble in water. My Regards
Why dialysis, you may get rid of template molecule by consecutive wash as batch mode extraction format (solid-liquid extraction)...
Btw, acetic acid diffuses into the bag as well but would not be as efficient and rapid as batch mode...
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