Hi,

I don't know their half life which could be cell type specific. You can determine their half-life by cycloheximide chase assay.

Dear Gustavo,

The DKK1 mRNA half-life was estimated at 2.4 hours. For more details, please see:

Expression of a protein involved in bone resorption, Dkk1, is activated by HTLV-1 bZIP factor through its activation domain

Nicholas Polakowski1*, Heather Gregory1, Jean-Michel Mesnard2 and Isabelle Lemasson1*

Retrovirology 2010, 7:61 doi:10.1186/1742-4690-7-61

http://www.retrovirology.com/content/7/1/61

Hoping this will be helpful,

Rafik

Dear Gustavo,

The DKK1 mRNA half-life was estimated at 2.4 hours. For more details, please see:

Expression of a protein involved in bone resorption, Dkk1, is activated by HTLV-1 bZIP factor through its activation domain

Nicholas Polakowski1*, Heather Gregory1, Jean-Michel Mesnard2 and Isabelle Lemasson1*

Retrovirology 2010, 7:61 doi:10.1186/1742-4690-7-61

http://www.retrovirology.com/content/7/1/61

Hoping this will be helpful,

Rafik

Dear Gustavo,

The DKK1 mRNA half-life was estimated at 2.4 hours. For more details, please see:

Expression of a protein involved in bone resorption, Dkk1, is activated by HTLV-1 bZIP factor through its activation domain

Nicholas Polakowski1*, Heather Gregory1, Jean-Michel Mesnard2 and Isabelle Lemasson1*

Retrovirology 2010, 7:61 doi:10.1186/1742-4690-7-61

http://www.retrovirology.com/content/7/1/61

Hoping this will be helpful,

Rafik